- Human C-type Lectin Domain Family 4, Member C (CLEC4C/BDCA-2/CD303) Is a Receptor for Asialo-galactosyl-oligosaccharides
[作者:Riboldi, E; Daniele, R; Parola, C; Inforzato, A; Arnold, PL; Bosisio, D; Fremont, DH; Bastone, A; Colonna, M; Sozzani, S,期刊:Journal of Biological Chemistry, 页码:35329-35333 , 文章类型: Article,,卷期:2011年286-41]
- Plasmacytoid dendritic cells are specialized in the production of type I interferon (type I IFN), which promotes antiviral and antitumor responses, as well as autoimmune disorders. Activation of type I IFN secretion depe...
- miR-155 Inhibits Expression of the MEF2A Protein to Repress Skeletal Muscle Differentiation
[作者:Seok, HY; Tatsuguchi, M; Callis, TE; He, AB; Pu, WT; Wang, DZ,期刊:Journal of Biological Chemistry, 页码:35339-35346 , 文章类型: Article,,卷期:2011年286-41]
- microRNAs (miRNAs) are 21-23-nucleotide non-coding RNAs. It has become more and more evident that this class of small RNAs plays critical roles in the regulation of gene expression at the post-transcriptional level. MEF2...
- Histone H1 Variants Are Differentially Expressed and Incorporated into Chromatin during Differentiation and Reprogramming to Pluripotency
[作者:Terme, JM; Sese, B; Millan-Arino, L; Mayor, R; Belmonte, JCI; Barrero, MJ; Jordan, A,期刊:Journal of Biological Chemistry, 页码:35347-35357 , 文章类型: Article,,卷期:2011年286-41]
- There are seven linker histone variants in human somatic cells (H1.0 to H1.5 and H1X), and their prevalence varies as a function of cell type and differentiation stage, suggesting that the different variants may have dis...
- Isolation of a TRAIL Antagonist from the Serum of HIV-infected Patients
[作者:Schnepple, DJ; Shepard, B; Bren, GD; Cummins, NW; Natesampillai, S; Trushin, S; Algeciras-Schimnich, A; Meng, XW; Sainski, AM; Rizza, SA; Kaufmann, SH; Badley, AD,期刊:Journal of Biological Chemistry, 页码:35742-35754 , 文章类型: Article,,卷期:2011年286-41]
- Virus-host interactions are characterized by the selection of adaptive mechanisms by which to evade pathogenic and defense mechanisms, respectively. In primary T cells infected with HIV, HIV infection up-regulates TNF-re...
- Epigenetic Control of the Host Gene by Commensal Bacteria in Large Intestinal Epithelial Cells
[作者:Takahashi, K; Sugi, Y; Nakano, K; Tsuda, M; Kurihara, K; Hosono, A; Kaminogawa, S,期刊:Journal of Biological Chemistry, 页码:35755-35762 , 文章类型: Article,,卷期:2011年286-41]
- Intestinal epithelial cells (IECs) are continuously exposed to large numbers of commensal bacteria but are relatively insensitive to them, thereby averting an excessive inflammatory reaction. We have previously reported ...
- Structural Basis for Inhibition of Cathepsin B Drug Target from the Human Blood Fluke, Schistosoma mansoni
[作者:Jilkova, A; Rezacova, P; Lepsik, M; Horn, M; Vachova, J; Fanfrlik, J; Brynda, J; McKerrow, JH; Caffrey, CR; Mares, M,期刊:Journal of Biological Chemistry, 页码:35770-35781 , 文章类型: Article,,卷期:2011年286-41]
- Schistosomiasis caused by a parasitic blood fluke of the genus Schistosoma afflicts over 200 million people worldwide. Schistosoma mansoni cathepsin B1 (SmCB1) is a gut-associated peptidase that digests host blood protei...
- Control of Proteobacterial Central Carbon Metabolism by the HexR Transcriptional Regulator A CASE STUDY IN SHEWANELLA ONEIDENSIS
[作者:Leyn, SA; Li, XQ; Zheng, QX; Novichkov, PS; Reed, S; Romine, MF; Fredrickson, JK; Yang, C; Osterman, AL; Rodionov, DA,期刊:Journal of Biological Chemistry, 页码:35782-35794 , 文章类型: Article,,卷期:2011年286-41]
- Background: Different regulatory strategies are utilized by bacteria to control central carbohydrate metabolism. Results: Transcriptional factor HexR is a global regulator of the central carbohydrate metabolism genes in ...
- Structures of Phytophthora RXLR Effector Proteins A CONSERVED BUT ADAPTABLE FOLD UNDERPINS FUNCTIONAL DIVERSITY
[作者:Boutemy, LS; King, SRF; Win, J; Hughes, RK; Clarke, TA; Blumenschein, TMA; Kamoun, S; Banfield, MJ,期刊:Journal of Biological Chemistry, 页码:35834-35842 , 文章类型: Article,,卷期:2011年286-41]
- Phytopathogens deliver effector proteins inside host plant cells to promote infection. These proteins can also be sensed by the plant immune system, leading to restriction of pathogen growth. Effector genes can display s...
- Protein Kinase A-mediated Serine 35 Phosphorylation Dissociates Histone H1.4 from Mitotic Chromosome
[作者:Chu, CS; Hsu, PH; Lo, PW; Scheer, E; Tora, L; Tsai, HJ; Tsai, MD; Juan, LJ,期刊:Journal of Biological Chemistry, 页码:35843-35851 , 文章类型: Article,,卷期:2011年286-41]
- Global histone H1 phosphorylation correlates with cell cycle progression. However, the function of site-specific H1 variant phosphorylation remains unclear. Our mass spectrometry analysis revealed a novel N-terminal phos...
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