- Ultrastructural and Biophysical Characterization of Hepatitis C Virus Particles Produced in Cell Culture
[作者:Gastaminza, P; Dryden, KA; Boyd, B; Wood, MR; Law, M; Yeager, M; Chisari, FV,期刊:Journal of virology, 页码:10999-11009 , 文章类型: Article,,卷期:2010年84-21]
- We analyzed the biochemical and ultrastructural properties of hepatitis C virus (HCV) particles produced in cell culture. Negative-stain electron microscopy revealed that the particles were spherical (similar to 40- to 7...
- Strain-Specific Differences in the Impact of Human TRIM5 alpha, Different TRIM5 alpha Alleles, and the Inhibition of Capsid-Cyclophilin A Interactions on the Infectivity of HIV-1
[作者:Battivelli, E; Lecossier, D; Matsuoka, S; Migraine, J; Clavel, F; Hance, AJ,期刊:Journal of virology, 页码:11010-11019 , 文章类型: Article,,卷期:2010年84-21]
- HIV-1 infectivity is strongly restricted by TRIM5 alpha from certain primate species but has been described as being only marginally susceptible to human TRIM5 alpha. In this study, we evaluated the effects of the modula...
- Toll-Like Receptor 4-Mediated Activation of p38 Mitogen-Activated Protein Kinase Is a Determinant of Respiratory Virus Entry and Tropism
[作者:Marchant, D; Singhera, GK; Utokaparch, S; Hackett, TL; Boyd, JH; Luo, ZS; Si, XN; Dorscheid, DR; McManus, BM; Hegele, RG,期刊:Journal of virology, 页码:11359-11373 , 文章类型: Article,,卷期:2010年84-21]
- Respiratory viruses exert a heavy toll of morbidity and mortality worldwide. Despite this burden there are few specific treatments available for respiratory virus infections. Since many viruses utilize host cell enzymati...
- Endogenous CD317/Tetherin Limits Replication of HIV-1 and Murine Leukemia Virus in Rodent Cells and Is Resistant to Antagonists from Primate Viruses
[作者:Goffinet, C; Schmidt, S; Kern, C; Oberbremer, L; Keppler, OT,期刊:Journal of virology, 页码:11374-11384 , 文章类型: Article,,卷期:2010年84-21]
- Human CD317 (BST-2/tetherin) is an intrinsic immunity factor that blocks the release of retroviruses, filoviruses, herpesviruses, and arenaviruses. It is unclear whether CD317 expressed endogenously in rodent cells has t...
- HIV Controllers with HLA-DRB1*13 and HLA-DQB1*06 Alleles Have Strong, Polyfunctional Mucosal CD4(+) T-Cell Responses
[作者:Ferre, AL; Hunt, PW; McConnell, DH; Morris, MM; Garcia, JC; Pollard, RB; Yee, HF; Martin, JN; Deeks, SG; Shacklett, BL,期刊:Journal of virology, 页码:11020-11029 , 文章类型: Article,,卷期:2010年84-21]
- A small percentage of human immunodeficiency virus (HIV)-infected individuals, termed elite controllers, are able to spontaneously control HIV replication in blood. As the gastrointestinal mucosa is an important site of ...
- Coexistence of Different Genotypes in the Same Bat and Serological Characterization of Rousettus Bat Coronavirus HKU9 Belonging to a Novel Betacoronavirus Subgroup
[作者:Lau, SKP; Poon, RWS; Wong, BHL; Wang, M; Huang, Y; Xu, HF; Guo, RT; Li, KSM; Gao, K; Chan, KH; Zheng, BJ; Woo, PCY; Yuen, KY,期刊:Journal of virology, 页码:11385-11394 , 文章类型: Article,,卷期:2010年84-21]
- Rousettus bat coronavirus HKU9 (Ro-BatCoV HKU9), a recently identified coronavirus of novel Betacoronavirus subgroup D, from Leschenault's rousette, was previously found to display marked sequence polymorphism among geno...
- Porcine Reproductive and Respiratory Syndrome Virus Inhibits Type I Interferon Signaling by Blocking STAT1/STAT2 Nuclear Translocation
[作者:Patel, D; Nan, YC; Shen, MY; Ritthipichai, K; Zhu, XP; Zhang, YJ,期刊:Journal of virology, 页码:11045-11055 , 文章类型: Article,,卷期:2010年84-21]
- Type I interferons (IFNs) IFN-alpha/beta play an important role in innate immunity against viral infections by inducing antiviral responses. Porcine reproductive and respiratory syndrome virus (PRRSV) inhibits the synthe...
- Proteasome Activator REG gamma Enhances Coxsackieviral Infection by Facilitating p53 Degradation
[作者:Gao, GA; Wong, J; Zhang, JC; Mao, I; Shravah, J; Wu, Y; Xiao, A; Li, XT; Luo, HL,期刊:Journal of virology, 页码:11056-11066 , 文章类型: Article,,卷期:2010年84-21]
- Coxsackievirus B3 (CVB3) is a small RNA virus associated with diseases such as myocarditis, meningitis, and pancreatitis. We have previously demonstrated that proteasome inhibition reduces CVB3 replication and attenuates...
- RNA Structures Required for Production of Subgenomic Flavivirus RNA
[作者:Funk, A; Truong, K; Nagasaki, T; Torres, S; Floden, N; Melian, EB; Edmonds, J; Dong, HP; Shi, PY; Khromykh, AA,期刊:Journal of virology, 页码:11407-11417 , 文章类型: Article,,卷期:2010年84-21]
- Flaviviruses are a group of single-stranded, positive-sense RNA viruses causing similar to 100 million infections per year. We have recently shown that flaviviruses produce a unique, small, noncoding RNA (similar to 0.5 ...
- Stably Expressed APOBEC3F Has Negligible Antiviral Activity
[作者:Miyagi, E; Brown, CR; Opi, S; Khan, M; Goila-Gaur, R; Kao, S; Walker, RC; Hirsch, V; Strebel, K,期刊:Journal of virology, 页码:11067-11075 , 文章类型: Article,,卷期:2010年84-21]
- APOBEC3F (A3F) is a member of the family of cytidine deaminases that is often coexpressed with APOBEC3G (A3G) in cells susceptible to HIV infection. A3F has been shown to have strong antiviral activity in transient-expre...
- A Conserved Domain in the Coronavirus Membrane Protein Tail Is Important for Virus Assembly
[作者:Arndt, AL; Larson, BJ; Hogue, BG,期刊:Journal of virology, 页码:11418-11428 , 文章类型: Article,,卷期:2010年84-21]
- Coronavirus membrane (M) proteins play key roles in virus assembly, through M-M, M-spike (S), and M-nucleocapsid (N) protein interactions. The M carboxy-terminal endodomain contains a conserved domain (CD) following the ...
- Cytotoxicity of ORF3 Proteins from a Nonpathogenic and a Pathogenic Porcine Circovirus
[作者:Chaiyakul, M; Hsu, K; Dardari, R; Marshall, F; Czub, M,期刊:Journal of virology, 页码:11440-11447 , 文章类型: Article,,卷期:2010年84-21]
- Porcine circovirus type 2 (PCV2) infection is associated with significant and serious swine diseases worldwide, while PCV1 appears to be a nonpathogenic virus. Previous studies demonstrated that the ORF3 protein of PCV2 ...
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