- A Small-Molecule Screening Strategy To Identify Suppressors of Statin Myopathy
[作者：WAGNER BRIDGET K; GILBERT TAMARA J; HANAI JUNICHI; IMAMURA SHINTARO; BODYCOMBE NICOLE E; BON ROBIN S; WALDMANN HERBERT; CLEMONS PAUL A; SUKHATME VIKAS P; MOOTHA VAMSI K,期刊：ACS CHEMICAL BIOLOGY, 页码：900-904 , 文章类型： Article，,卷期：2011年6-9]
- The reduction of plasma low-density lipoprotein levels by HMG-CoA reductase inhibitors, or statins, has had a revolutionary impact in medicine, but muscle-related side effects remain a dose-limiting toxicity in many pati...
- Trypanosomal Dihydrofolate Reductase Reveals Natural Antifolate Resistance
[作者：VANICHTANANKUL JARUNEE; TAWEECHAI SUPANNEE; YUVANIYAMA JIRUNDON; VILAIVAN TIRAYUT; CHITNUMSUB PENCHIT; KAMCHONWONGPAISAN SUMALEE; YUTHAVONG YONGYUTH,期刊：ACS CHEMICAL BIOLOGY, 页码：905-911 , 文章类型： Article，,卷期：2011年6-9]
- Dihydrofolate reductase (DHFR) is a potential drug target for Trypanosoma brucei, a human parasite, which is the causative agent for African sleeping sickness. No drug is available against this target, since none of the ...
- Identification of Ustilago maydis Aurora Kinase As a Novel Antifungal Target
[作者：TUECKMANTEL SANDRA; GREUL JOERG N; JANNING PETRA; BROCKMEYER ANDREAS; GRUETTER CHRISTIAN; SIMARD JEFFREY R; GUTBROD OLIVER; BECK MICHAEL E; TIETJEN KLAUS; RAUH DANIEL; SCHREIER PETER H,期刊：ACS CHEMICAL BIOLOGY, 页码：926-933 , 文章类型： Article，,卷期：2011年6-9]
- Infestation of crops by pathogenic fungi has continued to have a major impact by reducing yield and quality, emphasizing the need to identify new targets and. develop new agents to improve methods of crop protection. Her...
- Humanized Lewis-Y Specific Antibody Based Delivery of STAT3 siRNA
[作者：MA YUELONG; KOWOLIK CLAUDIA M; SWIDERSKI PIOTR M; KORTYLEWSKI MARCIN; YU HUA; HORNE DAVID A; JOVE RICHARD; CABALLERO OTAVIA L; SIMPSON ANDREW J G; LEE FOOKTHEAN; PILLAY VINOCHANI; SCOTT ANDREW M,期刊：ACS CHEMICAL BIOLOGY, 页码：962-970 , 文章类型： Article，,卷期：2011年6-9]
- The clinical application of siRNA is limited largely by the lack of efficient, cell-specific delivery systems. Antibodies are attractive delivery vehicles for targeted therapy due to their high specificity. In this study...
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