- Apico-basal elongation requires a drebrin-E-EB3 complex in columnar human epithelial cells
[作者：Bazellieres, E; Massey-Harroche, D; Barthelemy-Requin, M; Richard, F; Arsanto, JP; Le Bivic, A,期刊：Journal of cell science, 页码：919-931 , 文章类型： Article，,卷期：2012年125-4]
- Although columnar epithelial cells are known to acquire an elongated shape, the mechanisms involved in this morphological feature have not yet been completely elucidated. Using columnar human intestinal Caco2 cells, it w...
- Loss of alpha T-catenin alters the hybrid adhering junctions in the heart and leads to dilated cardiomyopathy and ventricular arrhythmia following acute ischemia
[作者：Li, JF; Goossens, S; van Hengel, J; Gao, EH; Cheng, L; Tyberghein, K; Shang, XY; De Rycke, R; van Roy, F; Radice, GL,期刊：Journal of cell science, 页码：1058-1067 , 文章类型： Article，,卷期：2012年125-4]
- It is generally accepted that the intercalated disc (ICD) required for mechano-electrical coupling in the heart consists of three distinct junctional complexes: adherens junctions, desmosomes and gap junctions. However, ...
- Syntaxin 1C, a soluble form of syntaxin, attenuates membrane recycling by destabilizing microtubules
[作者：Nakayama, T; Kamiguchi, H; Akagawa, K,期刊：Journal of cell science, 页码：817-830 , 文章类型： Article，,卷期：2012年125-4]
- Syntaxin 1C (STX1C), produced by alternative splicing of the stx1A gene, is a soluble syntaxin lacking a SNARE domain and a transmembrane domain. It is unclear how soluble syntaxin can control intracellular membrane traf...
- beta-Catenin-SOX2 signaling regulates the fate of developing airway epithelium
[作者：Hashimoto, S; Chen, HY; Que, JW; Brockway, BL; Drake, JA; Snyder, JC; Randell, SH; Stripp, BR,期刊：Journal of cell science, 页码：932-942 , 文章类型： Article，,卷期：2012年125-4]
- Wnt-beta-catenin signaling regulates cell fate during organ development and postnatal tissue maintenance, but its contribution to specification of distinct lung epithelial lineages is still unclear. To address this quest...
- The endonuclease Ankle1 requires its LEM and GIY-YIG motifs for DNA cleavage in vivo
[作者：Brachner, A; Braun, J; Ghodgaonkar, M; Castor, D; Zlopasa, L; Ehrlich, V; Jiricny, J; Gotzmann, J; Knasmuller, S; Foisner, R,期刊：Journal of cell science, 页码：1048-1057 , 文章类型： Article，,卷期：2012年125-4]
- The LEM domain (for lamina-associated polypeptide, emerin, MAN1 domain) defines a group of nuclear proteins that bind chromatin through interaction of the LEM motif with the conserved DNA crosslinking protein, barrier-to...
- Mitochondria and cell signalling
[作者：Tait, SWG; Green, DR,期刊：Journal of cell science, 页码：807-815 , 文章类型： Article，,卷期：2012年125-4]
- Mitochondria have long been considered as crucial organelles, primarily for their roles in biosynthetic reactions such as ATP synthesis. However, it is becoming increasingly apparent that mitochondria are intimately invo...
- Mitochondrial redox signalling at a glance
[作者：Collins, Y; Chouchani, ET; James, AM; Menger, KE; Cocheme, HM; Murphy, MP,期刊：Journal of cell science, 页码：801-806 , 文章类型： Editorial Material，,卷期：2012年125-4]
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- The HIF1 target gene NOX2 promotes angiogenesis through urotensin-II
[作者：Diebold, I; Petry, A; Sabrane, K; Djordjevic, T; Hess, J; Gorlach, A,期刊：Journal of cell science, 页码：956-964 , 文章类型： Article，,卷期：2012年125-4]
- Urotensin-II (U-II) has been considered as one of the most potent vasoactive peptides, although its physiological and pathophysiological role is still not finally resolved. Recent evidence suggests that it promotes angio...
- N-cadherin expression level modulates integrin-mediated polarity and strongly impacts on the speed and directionality of glial cell migration
[作者：Camand, E; Peglion, F; Osmani, N; Sanson, M; Etienne-Manneville, S,期刊：Journal of cell science, 页码：844-857 , 文章类型： Article，,卷期：2012年125-4]
- Perturbation of cell polarity is a hallmark of cancer cells. In carcinomas, loss of epithelial E-cadherin contributes to the loss of cell polarity and promotes epithelial-mesenchymal transition and carcinoma infiltration...
- The microtubule poison vinorelbine kills cells independently of mitotic arrest and targets cells lacking the APC tumour suppressor more effectively
[作者：Klotz, DM; Nelson, SA; Kroboth, K; Newton, IP; Radulescu, S; Ridgway, RA; Sansom, OJ; Appleton, PL; Nathke, IS,期刊：Journal of cell science, 页码：887-895 , 文章类型： Article，,卷期：2012年125-4]
- Colorectal cancers commonly carry truncation mutations in the adenomatous polyposis coli (APC) gene. The APC protein contributes to the stabilization of microtubules. Consistently, microtubules in cells lacking APC depol...
- Oxidative-stress-induced nuclear to cytoplasmic relocalization is required for Not4-dependent cyclin C destruction
[作者：Cooper, KF; Scarnati, MS; Krasley, E; Mallory, MJ; Jin, CY; Law, MJ; Strich, R,期刊：Journal of cell science, 页码：1015-1026 , 文章类型： Article，,卷期：2012年125-4]
- The yeast cyclin-C-Cdk8p kinase complex represses the transcription of a subset of genes involved in the stress response. To relieve this repression, cyclin C is destroyed in cells exposed to H2O2 by the 26S proteasome. ...
- Plk2 regulates centriole duplication through phosphorylation-mediated degradation of Fbxw7 (human Cdc4)
[作者：Cizmecioglu, O; Krause, A; Bahtz, R; Ehret, L; Malek, N; Hoffmann, I,期刊：Journal of cell science, 页码：981-992 , 文章类型： Article，,卷期：2012年125-4]
- Polo-like kinases (Plks) perform crucial functions during mitosis, cytokinesis and centriole duplication. Plk2 is activated in early G1 phase and is involved in the reproduction of centrosomes. However, the mechanisms un...
- Translation of the cell adhesion molecule ALCAM in axonal growth cones - regulation and functional importance
[作者：Thelen, K; Maier, B; Faber, M; Albrecht, C; Fischer, P; Pollerberg, GE,期刊：Journal of cell science, 页码：1003-1014 , 文章类型： Article，,卷期：2012年125-4]
- ALCAM is a cell adhesion molecule that is present on extending axons and has been shown to be crucial for elongation and navigation of retinal ganglion cell (RGC) axons. In the present study, we show that ALCAM mRNA is p...
- Homotypic RANK signaling differentially regulates proliferation, motility and cell survival in osteosarcoma and mammary epithelial cells
[作者：Beristain, AG; Narala, SR; Di Grappa, MA; Khokha, R,期刊：Journal of cell science, 页码：943-955 , 文章类型： Article，,卷期：2012年125-4]
- RANKL (receptor activator of NF-kappa B ligand) is a crucial cytokine for regulating diverse biological systems such as innate immunity, bone homeostasis and mammary gland differentiation, operating through activation of...
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